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Sulfathiazole (CAS 72-14-0) is a small-molecule inhibitor targeting dihydropteroate synthase (DHPS) It is designed to competitively inhibit bacterial folic acid synthesis thereby disrupting the folate pathway and impeding microbial growth Sulfathiazole exerts its biological activity primarily through inhibition of DHPS In in vitro studies sulfathiazole demonstrates bacteriostatic inhibition with IC50 values ranging from low to medium micromolar concentrations depending on specific bacterial strains and experimental conditions Based on these pharmacological properties sulfathiazole holds research potential in investigating antibacterial resistance metabolic pathways of pathogens and enzyme-substrate interactions in microbiological and biochemical research
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Cyclopentyl phenyl ketone is an organic synthesis intermediate used as a building block in medicinal chemistry and related research. It is a ketone (CAS 5422-88-8) with molecular formula C12H14O and a molecular weight of 174.24 g/mol. Supplied as a liquid with high reported purity, the compound is intended for research and synthesis applications; safety data and analytical documentation are available.
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Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GSK2983559 active metabolite (RIPK2-IN-1) is a potent selective receptor-interacting protein-2 (RIP2) kinase inhibitor. purity: 98%
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Benzcyclane (Benzcyclan) is an inhibitor of platelet aggregation and also a vasodilator that can be used in a variety of peripheral circulation disorders. purity: 99%
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mGluR3 modulator-1 is a small-molecule modulator of the metabotropic glutamate receptor 3 (mGluR3) intended for research use. It demonstrates activity in cellular calcium mobilization assays (EC50 = 1-10 μM) and is supplied with a reported high purity and defined molecular properties suitable for in vitro pharmacology and receptor profiling studies.
Modulates mGluR3 receptor activity in cell-based assays.
Demonstrated EC50 of 1-10 μM in HEK293T-mGluR-Gqi5 calcium mobilization assay.
High purity suitable for research applications.
Available in small mass packages for screening and assay work.
Includes chemical identifiers for traceability, such as CAS 374548-18-2.
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Sulfapyridine (144-83-2) is a small-molecule inhibitor targeting bacterial dihydropteroate synthase It functions by inhibiting this enzyme thus blocking folic acid synthesis and suppressing bacterial growth Sulfapyridine exerts its biological activity primarily through inhibition of bacterial dihydropteroate synthase In in vitro studies sulfapyridine demonstrates inhibitory activity with IC50 values typically ranging from approximately 5 g/mL to 20 g/mL depending on the bacterial strain and assay conditions Based on these pharmacological properties sulfapyridine holds research potential in antimicrobial susceptibility testing investigations of bacterial resistance mechanisms and studies of bacterial folate pathway enzymes
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Chemical. CAS 1143863-69-7. Formula C15H11FO2. MW 242.2. Highly selective metastasis inhibitor in vitro. Binds to and stabilizes Cdc37-HSP90beta heterocomplexes, consequently blocking its function and inhibiting cancer cell motility. Does not bind to Cdc37 or HSP90beta alone. Inhibits cancer metastasis in vivo in murine models of human prostate and breast cancer. Shown to exhibit a complete lack of cellular cytotoxicity and systemic toxicity.
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AMPA receptor modulator-1 can be activated by glutamate thereby modulating ion channels. purity: 98%
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